View source for Chemistry:2-Methyl-2-propyl-1,3-propanediol

{{Short description|Chemical compound}}
{{Drugbox
| IUPAC_name = 2-methyl-2-propyl-1,3-propanediol
| image = 2methyl2propylpropanediol_structure.png

<!--Clinical data-->
| tradename =  
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<!--Pharmacokinetic data-->
| bioavailability =  
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<!--Identifiers-->
| CAS_number = 78-26-2
| ATC_prefix = 
| ATC_suffix = 
| PubChem = 66220
| ChemSpiderID = 59605
| UNII = YLM5KRU0P4
| ChEBI = 
| KEGG = 

<!--Chemical data-->
| C=7 | H=16 | O=2 
| smiles = CCCC(C)(CO)CO
| StdInChI = 1S/C7H16O2/c1-3-4-7(2,5-8)6-9/h8-9H,3-6H2,1-2H3
| StdInChIKey = JVZZUPJFERSVRN-UHFFFAOYSA-N
| melting_point = 56-59
}}

'''2-Methyl-2-propyl-1,3-propanediol''' ('''MPP''') is a simple alkyl [[Chemistry:Diol|diol]] which has [[Chemistry:Sedative|sedative]], [[Chemistry:Anticonvulsant|anticonvulsant]] and [[Chemistry:Muscle relaxant|muscle relaxant]] effects. It is both a synthetic precursor to, and an [[Biology:Active metabolite|active metabolite]] of the tranquilizers [[Chemistry:Meprobamate|meprobamate]] and [[Chemistry:Carisoprodol|carisoprodol]], as well as other derivatives.<ref name="pmid23924275">{{cite journal | vauthors = Wang G, Lu Q | title = A nitrate ester of sedative alkyl alcohol improves muscle function and structure in a murine model of Duchenne muscular dystrophy | journal = Molecular Pharmaceutics | volume = 10 | issue = 10 | pages = 3862–70 | date = October 2013 | pmid = 23924275 | doi = 10.1021/mp400310r }}</ref><ref>{{cite journal | vauthors = Yale HL, Pribyl EJ, Braker W, Bergeim FH, Lott WA | title = Muscle-relaxing Compounds Similar to 3-(o-Toloxy)-1, 2-propanediol. 1 I. Aromatic Ethers of Polyhydroxy Alcohols and Related Compounds. | journal = Journal of the American Chemical Society | date = August 1950 | volume = 72 | issue = 8 | pages = 3710–6 | doi = 10.1021/ja01164a108 }}</ref><ref>{{cite patent | inventor = Kato K, Tsukamoto K | title = 2-(2-Alkenyl)-1,3-propanediols and preparation of 2,2-disubstituted-1,3-propanediols | gdate = 1997 | country = JP | number = 09031000 }}</ref><ref name="pmid30134081">{{cite journal | vauthors = Kaithal A, Hölscher M, Leitner W | title = Catalytic Hydrogenation of Cyclic Carbonates using Manganese Complexes | journal = Angewandte Chemie International Edition in English| volume = 57 | issue = 41 | pages = 13449–13453 | date = October 2018 | pmid = 30134081 | pmc = 6221167 | doi = 10.1002/anie.201808676 }}</ref>

==See also==
* [[Chemistry:1,4-Butanediol|1,4-Butanediol]]
* [[Chemistry:1,6-Dioxecane-2,7-dione|1,6-Dioxecane-2,7-dione]]
* [[Chemistry:1-Ethynylcyclohexanol|1-Ethynylcyclohexanol]]
* [[Chemistry:Mephenesin|Mephenesin]]
* [[Chemistry:Prenderol|Prenderol]]

==References==
{{Reflist}}

{{Alcohols}}
{{Sedatives}}

{{DEFAULTSORT:Methylpropylpropanediol}}
[[Category:Muscle relaxants]]


{{Sourceattribution|2-Methyl-2-propyl-1,3-propanediol}}