View source for Biology:ARID3B

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''AT-rich interactive domain-containing protein 3B''' is a [[Biology:Protein|protein]] that in humans is encoded by the ''ARID3B'' [[Biology:Gene|gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ARID3B AT rich interactive domain 3B (BRIGHT-like)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10620}}</ref>

== Function ==

This gene encodes a member of the [[Biology:ARID domain|ARID]] (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.<ref name="entrez" />

== References ==
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== Further reading ==
{{refbegin | 2}}
* {{cite journal | vauthors = Kortschak RD, Tucker PW, Saint R | title = ARID proteins come in from the desert | journal = Trends in Biochemical Sciences | volume = 25 | issue = 6 | pages = 294–9 | date = Jun 2000 | pmid = 10838570 | doi = 10.1016/S0968-0004(00)01597-8 }}
* {{cite journal | vauthors = Numata S, Claudio PP, Dean C, Giordano A, Croce CM | title = Bdp, a new member of a family of DNA-binding proteins, associates with the retinoblastoma gene product | journal = Cancer Research | volume = 59 | issue = 15 | pages = 3741–7 | date = Aug 1999 | pmid = 10446990 }}
* {{cite journal | vauthors = Liao TT, Hsu WH, Ho CH, Hwang WL, Lan HY, Lo T, Chang CC, Tai SK, Yang MH | title = let-7 Modulates Chromatin Configuration and Target Gene Repression through Regulation of the ARID3B Complex | journal = Cell Reports | volume = 14 | issue = 3 | pages = 520–33 | year = 2016 | pmid = 26776511 | doi = 10.1016/j.celrep.2015.12.064 | doi-access = free }}
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== External links ==
* {{MeshName|ARID3B+protein,+human}}
* {{UCSC gene info|ARID3B}}

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{{Transcription factors|g0}}

[[Category:Transcription factors]]

{{Sourceattribution|ARID3B}}